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Evaluation of saliva as a complementary technique to the diagnosis of COVID-19:a systematic review

2021

Background Infectious disease coronavirus 2019 (COVID-19) is caused by the SARS-CoV-2 virus, and it mainly affects the upper respiratory tract. The gold standard for its diagnosis is real-time reverse transcription polymerase chain reaction (RT-qPCR) performed on a nasopharyngeal swab. In contrast, testing saliva has significant advantages as a diagnostic method. Material and Methods We searched for articles evaluating saliva as a diagnostic method for COVID-19 on the PUBMED/MEDLINE, WEB OF SCIENCE, COCHRANE, and SCIELO platforms. We initially found 233 articles and 20 were selected for inclusion following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol: 18 c…

Adultmedicine.medical_specialtySalivaAsiaMEDLINELoop-mediated isothermal amplificationReviewAsymptomaticSensitivity and Specificityvirtual microscopy03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansSalivaGeneral Dentistryoral histopathologyUNESCO:CIENCIAS MÉDICASOral Medicine and Pathologybusiness.industrySARS-CoV-2questionnaireCOVID-19remote online learning030206 dentistryGold standard (test)Reverse transcription polymerase chain reactionEuropeSystematic reviewCross-Sectional StudiesOtorhinolaryngologyMolecular Diagnostic TechniquesInfectious disease (medical specialty)Surgerymedicine.symptombusinessdental undergraduate studentsNucleic Acid Amplification Techniques
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